Difference Between  plasma and serum


1) Plasma : 
  • Plasma is Obtained by centrifugation of the anticoagulant added to blood
  • It contains all clotting factors except calcium ions
  • It is used for coagulation studies like PT,APTT,TT








2) Serum
  • Serum is obtained when blood undergoes clotting 
  • It does not contain fibrinogen,prothrombin F.V,VII,VIII,IX,X,XI and XII which have been used in clotting
  • It is used for estimation of various biochemical parameters and serum enzymes like SGOT,SGPT,S.Alkaline phosphatase,S.Uric acid,S.Electrolytes etc.